A motorcyclist, critically injured in a crash on the Gold Coast has died in hospital.

A car and motorbike collided in the southbound lanes of the M1 at Molendinar around 12.30pm on Thursday.

The 51-year-old rider of the motorcycle was rushed to the Gold Coast University Hospital.

However, the man from Pimpama succumbed to his injuries.

Three occupants of the vehicle, a 20-year-old man, a 45-year-old man and a 67-year-old man were uninjured.

The Forensic Crash Unit is investigating the accident.

Police are appealing for witnesses or anyone with dashcam footage to contact them.

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