Thieves are on the run following an early morning break-in at a chemist on the northern Gold Coast.

Four people allegedly broke into a pharmacy located in the Ormeau Shopping Village around 1.45am on Wednesday.

Queensland Police said the brazen group smashed the front glass doors to gain entry to the shop.

They stole an unknown amount of medication before fleeing the scene in a Kia Sportage, believed to have been stolen.

Investigations are underway.

If you have information for Police, please contact Policelink on 131 444 or provide information using their online form 24 hours per day.

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You can also report information about crime anonymously to Crime Stoppers by calling 1800 333 000 or via crimestoppersqld.com.au 24 hours per day. Crime Stoppers is a registered charity and community volunteer organisation.

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