Fire investigators are working to piece together the cause of a massive house fire in Nerang.

The blaze ripped through a two-storey home along Mount Nathan Road around 9.30pm on Wednesday.

Multiple fire crews worked to battle the flames and had the fire under control by 10pm.

Despite their efforts, about 80 per cent of the property sustained structure collapse.

However, thankfully no one was home at the time so no one was injured.

Investigations are ongoing.

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